In CKD with secondary hyperparathyroidism, which lab pattern is typically seen?

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Study for the NCLEX Genitourinary Disorders Test. Prepare with flashcards and multiple choice questions, each with hints and explanations. Get ready for your exam!

Multiple Choice

In CKD with secondary hyperparathyroidism, which lab pattern is typically seen?

Explanation:
In CKD, the kidneys lose the ability to excrete phosphate and to activate vitamin D. Phosphate accumulates in the blood (hyperphosphatemia), and the reduced active vitamin D lowers calcium absorption from the gut, leading to lower calcium levels (hypocalcemia). The drop in calcium stimulates the parathyroid glands to release more PTH, causing secondary hyperparathyroidism. So the typical lab pattern is high phosphate, low calcium, and high PTH. This combination also contributes to bone problems seen with kidney disease (renal osteodystrophy).

In CKD, the kidneys lose the ability to excrete phosphate and to activate vitamin D. Phosphate accumulates in the blood (hyperphosphatemia), and the reduced active vitamin D lowers calcium absorption from the gut, leading to lower calcium levels (hypocalcemia). The drop in calcium stimulates the parathyroid glands to release more PTH, causing secondary hyperparathyroidism. So the typical lab pattern is high phosphate, low calcium, and high PTH. This combination also contributes to bone problems seen with kidney disease (renal osteodystrophy).

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